Kharbediya Vakhtang Khvichevich – Head of the Children’s Oncology Rehabilitation Department of the Federal Children’s Rehabilitation Center “Korablik”, a structural unit of the Russian Children’s Clinical Hospital branch of the N.I. Pirogov Russian National Research Medical University, 4a Vysotnaya Street, 142114 Podolsk, Moscow Region, Russian Federation; e-mail: kharbediya1992@mail.ru; https://orcid.org/0000-0001-7574-335X.
Sergeenko Elena Yuryevna – Grand PhD in Medical sciences, Professor, Head of the Department of Rehabilitation and Physiotherapy, Russian National Research Medical University named after N.I. Pirogov, 1 Ostrovityanova Street, 6 building, 117513 Moscow, Russian Federation; e-mail: elenarsmu@mail.ru; https:// orcid.org/0000-0001-7882-1317.
Glazyrina Anastasia Aleksandrovna – PhD in Medical sciences, Head of the Federal Children’s Rehabilitation Center “Korablik”, a structural unit of the Russian Children’s Clinical Hospital branch of the N.I. Pirogov Russian National Research Medical University, 117 Leninsky Avenue, 119571 Moscow, Russian Federation; e-mail: glazyrina.a.a@rambler.ru; https:// orcid.org/0000-0002-2397-3484.
Petryaykina Elena Efimovna – Professor, Director of the Russian Children’s Clinical Hospital, branch of the Russian National Research Medical University named after N.I. Pirogov, 117 Leninsky Avenue, 119571 Moscow, Russian Federation; https://orcid.org/0000-0002-8520-2378.
In the heading: Rewiews
Year: 2026 Volume: 8 Journal number: 1
Pages: 120-130
Article type: scientific and practical
UDC: 615.825
DOI: 10.26211/2658-4522-2026-8-1-120-130
Introduction. Combined chemo-radiation treatment of children with tumor diseases of the hematopoietic and lymphoid tissues is often aggravated by multiple organ toxicity, which in some cases can lead to the development of motor and functional disorders.
Aim. The aim of this literature review is to assess the effect of therapeutic physical culture in children with hemoblastoses at the stages of antitumor drug treatment on activity indicators and motor functions based on the analysis of the indicators of the International Classification of Functioning domains.
Materials and methods. During the work, a search was conducted in 10 medical literature databases for the period from 2015 to 2025, using data from 19 studies: 11 randomized clinical trials, 2 controlled clinical trials, and 6 cohort studies.
Results. The main and comparison groups included 508 children with hemoblastoses. Intergroup results of randomized clinical trials and controlled clinical trials confirmed that exercise therapy had a positive effect on reducing the level of tumor-associated fatigue during the intensive and maintenance phases of chemotherapy, increased physical activity and strength, and improved tolerance to aerobic exercise.
During long-term observation in the remission stage, patients with hemoblastoses showed continued positive dynamics in compensation and leveling of motor and functional disorders.
Discussion. In the future, it is necessary to conduct multicenter randomized studies with the unification of functional status assessment methods based on the domains of the International Classification of Functioning, which will allow for an objective evaluation of the impact of therapeutic physical training on various aspects of physical development and psychosocial well-being of children with hemoblastoses at different stages of antitumor treatment.
Summary. The presented results, obtained on the basis of analysis of literature review data, indicate a positive effect of exercise therapy on functional and motor disorders in children with hemoblastoses.
Keywords: exercise therapy, hemoblastosis, leukemia, lymphoma, oncology, rehabilitation, restorative treatment
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