Scientometric analysis of physical methods for skin remodeling


Gritskova Inna Alexandrovna, dermatovenerologist, clinic of skin and venereal diseases, S.M. Kirov Military Medical Academy, 6 Academician Lebedeva, St. Petersburg, 194044, Russian Federation; tel.: +79372454234; e-mail:;

Ponomarenko Inga Gennadievna, Grand PhD in Medical sciences, Associate Professor of Department of Physical and Rehabilitation Medicine, North-Western State Medical University named after I.I. Mechnikov, 47 Piskarevsky Ave., St. Petersburg, 195067, Russian Federation; Associate Professor of the Department of Skin and Venereal Diseases, S.M. Kirov Military Medical Academy, 6 Akademika Lebedeva Str., St. Petersburg, 194044, Russian Federation; tel.: +79218886675; e-mail:; /0000-0001-6550-6940.

Shamsutdinova Diana Startovna, dermatocosmetologist, Albrecht Federal Scientific Centre of Rehabilitation of the Disabled, 50 Bestuzhevskaya Str., St. Petersburg, 195067, Russian Federation, tel.:+7911089679; e-mail:; /0000-0002-4567-2023.

In the heading: Rewiews

Year: 2023 Volume: 5 Journal number: 2 

Pages: 87-97

Article type: scientific and practical

UDC: 616.5-003.923

DOI: 10.26211/2658-4522-2023-5-2-87-97


Introduction. In modern society, high requirements are put forward for the quality of medical care in the field of aesthetic medicine, since the beauty of a person has a significant impact on the quality of life and self-esteem of patients. Mankind has not learned how to stop and prevent the aging process of the skin; this is the reason for the constant development of new and improvement of existing methods for correcting involutive skin changes and manifestations of photo- and chronoaging. In this regard, the verification of the therapeutic effects of physical methods of skin relief remodeling, based on the data of domestic and international evidence-based scientific literature, is an urgent task of public health.

Aim. Scientometric analysis of existing skin remodeling methods based on evidence-based research data.

Materials and methods. Conducting a scientometric analysis of effective physical methods of skin remodeling based on data from meta-analyses, systematic reviews and randomized clinical trials with the highest levels of evidence. Electronic databases (PEDro, Google Scholar, PubMed) and systematic review databases (Cochrane database) were used.

Results. The structure of the scientometric data stream of sources containing evidence-based data on the use of physical methods of skin remodeling is dominated by technologies associated with the use of high-intensity laser therapy (HILT 42.3%), microfocused ultrasound (MFU 17.4%), low-intensity laser therapy (LLT 10.1% ), fractional radiofrequency lifting (RF-lifting 8.1%), high-intensity light pulse (IPL — technology 3.2%), hyperbaric oxygen therapy (HBO 3%), mechanical stimulation (2.5%), combined methods of physical impact (13.4 %).
These technologies cause significant clinical effects and clinically and histologically proven remodeling of the skin matrix.

Discussion. Taking into account the constantly developing industry of aesthetic medicine technologies, it is necessary to regularly analyze the results of studies of a high methodological level, presented in domestic and international abstract databases. The result of the scientometric analysis of literature sources can be the development of further clinical recommendations for the practical application of physical methods for correcting age-related and involutive skin changes.

Summary. In the course of the analysis, among the abundance of physiotherapeutic methods, the most effective in the matter of skin remodeling, which have a high evidence base, were identified. Conducting periodic scientometric analyzes of domestic and foreign research bases with high levels of evidence is the basis for the formation of relevant and high-quality clinical recommendations

Keywords: , , , ,

Download the full text of the article

List of cited literature:

1. Silina EV, Manturova NE, Morgulis NV, Stupin VA. Fiziologiya stareniya kozhi [Physiology of skin aging]. Plasticheskaya hirurgiya i esteticheskaya medicina [Plastic Surgery and Aesthetic Medicine]. 2020;(2):40-5. DOI: 10.17116/plast.hirurgia202002140. (In Russian).

2. Presnova TE, Glotova NS, Karacheva YV et al. Faktory, vliyayushchie na starenie kozhi [Factors influencing skin aging]. Vestnik SurGU. Medicina [Vestnik SurGU. Medicine]. 2019; No. 3(41): 63-9. (In Russian).

3. Pan YF, Wang YY, Chen JW, Fan YM. Mitochondrial metabolism’s effect on epigenetic change and aging. Hereditas. 2019;41(10):893-904. DOI: 10.16288/j.yczz.19-065.

4. Xu K, Guo Y, Li Z, Wang Z. Aging Biomarkers and Novel Targets for AntiAging Interventions. Adv Exp Med Biol. 2019;1178:39-56. DOI: 10.1007/978-3-030-25650-0_3.

5. Koltover VK. Free Radical Timer of Aging: from Chemistry of Free Radicals to Systems Theory of Reliability // Curr Aging Sci. 2017;10(1):12-7.

6. Moldogazieva NT, Mokhosoev IM, Mel’nikova TI, Porozov YB, Terentiev AA. Oxidative stress and advanced lipoxidation and glycation end products (ALEs and AGEs) in aging and age-related diseases // Oxid Med Cell Longev. 2019;3085756. DOI: 10.1155/2019/3085756.

7. Bocheva G, Slominski R, Slominski A. Neuroendocrine Aspects of Skin Aging. Int. J of Molecular Sciences. 2019; 20(11):2798.

8. Burke KE. Mechanisms of aging and development-A new understanding of environmental damage to the skin and prevention with topical antioxidants // Mech Ageing Dev. 2018;172:123-30. DOI: 10.1016/j.mad.2017.12.003.

9. Askhakov MS, Chebotarev vV. Ul’trafioletovoe obluchenie kozhi i fotoprotekciya v kosmetologii [Ultraviolet irradiation of the skin and photoprotection in cosmetology]. Nauchnoe obozrenie. Medicinskie nauki [Scientific Review. Medical Sciences]. 2017;6:5-13.

10. Kurganskaya IG, Klyuchareva SV, Cherkashina IV. Vysokointensivnaya lazeroterapiya patologicheskih rubcov kozhi: naukometricheskij analiz dokazatel’nyh issledovanij [High-intensity laser treatment in pathological skin scarrings: a scientometric analysis of evidence-based studies]. Kremlevskaya medicina. Klinicheskij vestnik [Kremlin medicine. Clinical Bulletin]. 2021; 1:100-5. (In Russian).

11. Shelygin KV, Lozhkina LI. Naukometricheskoe issledovanie statej, posvyashchyonnyh izucheniyu effektivnosti zdravoohraneniya v Rossii [Scientometric study of articles devoted to the study of the effectiveness of health care in Russia]. Ekologiya cheloveka [Human Ecology]. 2022, 29(8):547-61. (In Russian).

12. Chen R, Wargo JJ, Williams A, et al. Single Ablative Fractional Resurfacing Laser Treatment For Forearm Actinic Keratoses: 6-Month Follow-Up Data From An Intrapatient Comparison Between Treated and Untreated Sites. Lasers Surg Med. 2020;52(1):84-7. DOI: 10.1002/lsm.23175.

13. Borges J, Cuzzi T, Mandarim-de-Lacerda CA, Manela-Azulay M. Fractional Erbium laser in the treatment of photoaging: randomized comparative, clinical and histopathological study of ablative (2940nm) vs. non-ablative (1540nm) methods after 3 months. An Bras Dermatol. 2014;89(2):250-8. DOI: 10.1590/abd1806-4841.20142370.

14. Beigvand HH, Razzaghi M, Rostami-Nejad M. et al. Assessment of Laser Effects on Skin Rejuvenation. J Lasers Med Sci. 2020;11(2):212-9. DOI: 10.34172/jlms.2020.35.

15. Gawdat H, Allam RSHM, Hegazy R et al. Comparison of the efficacy of Fractional Radiofrequency Microneedling alone and in combination with platelet-rich plasma in neck rejuvenation: a clinical and optical coherence tomography study. J Cosmet Dermatol.2022;21(5):2038-45. DOI: 10.1111/jocd.14331.

16. Khan U, Khalid NA. Systematic Review of the Clinical Efficacy of Micro-Focused Ultrasound Treatment for Skin Rejuvenation and Tightening. Cureus. 2021;13(12): e20163. DOI: 10.7759/cureus.20163.

17. Fabi SG. Noninvasive skin tightening: focus on new ultrasound techniques // Clin Cosmet Investig Dermatol. 2015; 8: 47-52. DOI: 10.2147/CCID.S69118.

18. Ablon G. Phototherapy with Light Emitting Diodes: Treating a Broad Range of Medical and Aesthetic Conditions in Dermatology. J Clin Aesthet Dermatol. 2018;11(2):21-7.

19. Humbert P, Fanian F, Lihoreau T et al. Mecano-Stimulation of the skin improves sagging score and induces beneficial functional modification of the fibroblasts: clinical, biological, and histological evaluations. Clin Interv Aging. 2015; 10:387-403. DOI: 10.2147/CIA.S69752.

20. Avci P, Gupta A, Sadasivam M et al. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Semin Cutan Med Surg. 2013; 32(1):41-52.

21. Hachmo Y, Hadanny А, Mendelovic S. The effect of hyperbaric oxygen therapy on the pathophysiology of skin aging: a prospective clinical trial. Aging (Albany NY). 2021;13(22):24500-10. DOI: 10.18632/aging.203701.

22. GOST R 56034-2014. Klinicheskie rekomendacii (protokoly lecheniya). Obshchie polozheniya.[Clinical recommendations (treatment protocols). General provisions]. M., 2014. 23p. (In Russian).

23. Prikaz Ministerstva zdravoohraneniya Rossijskoj Federacii ot 28.02.2019 N 103n [Order of the Ministry of Health of the Russian Federation N 103n of February 28, 2019]. Available at: Document/ View/0001202206060031. (In Russian).

24. Wunsch A, Matuschka K. A controlled trial to determine the efficacy of red and near-infrared light treatment in patient satisfaction, reduction of fine lines, wrinkles, skin roughness, and intradermal collagen density increase. Photomed Laser Surg. 2014;32(2):93-100. DOI: 10.1089/pho.2013.3616.

25. Araujo AR, Soares VP, Silva FS, Moreira Tda S. Radiofrequency for the treatment of skin laxity: mith or truth. An Bras Dermatol. 2015;90(5):707-21. DOI: 10.1590/abd1806-4841.20153605.

26. Weiss RA, McDaniel DH, Weiss MA et al. Safety and efficacy of a novel diffractive lens array using a picosecond 755 nm alexandrite laser for treatment of wrinkles. Lasers Surg Med.2017;49(1):40-4. DOI: 10.1002/lsm.22577.

27. Bernstein EF, Bloom JD. Safety and Efficacy of Bilateral Submental Cryolipolysis with Quantified 3-Dimensional Imaging of Fat Reduction and Skin Tightening. JAMA Facial Plast Surg. 2017;19(5):350-7. DOI: 10.1001/jamafacial.2017.0102.

28. Truchuelo MT, Vitale M. A cosmetic treatment based on the secretion of Cryptomphalus aspersa 40% improves the clinical results after the use of nonablative fractional laser in skin aging. J Cosmet Dermatol. 2020;19(3):622-8. DOI: 10.1111/jocd.13052.

29. Li Y, Liao M, Zhu Y. Hyaluronic Acid Compound Filling Plus Mesotherapy vs Botulinum Toxin A for the Treatment of Horizontal Neck Lines: A Multicenter, Randomized, Evaluator-Blinded, Prospective Study in Chinese Subjects. Aesthet Surg J. 2022;42(4):230-41. DOI: 10.1093/asj/sjab387.

www.xhamaster actress priyamani sex videos chuda chudi bangla chuda chudi keral sex sex in tamil youtube sex between young couple desi sex scenes sunnyleone hot sex baglabf
sex movies com hind sexi video desi sexey video tamil sex video songs mms x sexihotgirl suny leone porn chennai girl escorts xvideos office tamil xxxx videos fittrip snyper 6ft in cm
ben 10 sex video videos of boys and girls indian college girl porn videos xnxnxxx desi chudai vedio hot girl sexy sexgaral nexxx bf videos chodne ka